BDBM50367061 NALORPHINE::NALORPHINE HYDROCHLORIDE

SMILES O[C@H]1C=C[C@H]2[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC=C)c45

InChI Key InChIKey=UIQMVEYFGZJHCZ-SSTWWWIQSA-N

Data  8 KI  13 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50367061   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50367061(NALORPHINE | NALORPHINE HYDROCHLORIDE)
Affinity DataIC50:  48nMAssay Description:Inhibition of specific binding of [125I]-PIPAG to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50367061(NALORPHINE | NALORPHINE HYDROCHLORIDE)
Affinity DataIC50:  735nMAssay Description:Inhibition of specific binding of [125I]PIPAG to sigma receptor in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50367061(NALORPHINE | NALORPHINE HYDROCHLORIDE)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of specific binding of [125I]-PIPAG to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50367061(NALORPHINE | NALORPHINE HYDROCHLORIDE)
Affinity DataIC50:  2.85E+3nMAssay Description:Inhibition of specific binding of [3H]3-PPP to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50367061(NALORPHINE | NALORPHINE HYDROCHLORIDE)
Affinity DataIC50:  625nMAssay Description:Inhibition of specific binding of [3H]3-PPP to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50367061(NALORPHINE | NALORPHINE HYDROCHLORIDE)
Affinity DataIC50:  93nMAssay Description:Inhibition of specific binding of [3H]3-PPP to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50367061(NALORPHINE | NALORPHINE HYDROCHLORIDE)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of specific binding of [125I]-PIPAG to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50367061(NALORPHINE | NALORPHINE HYDROCHLORIDE)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of specific binding of [3H]NANM of sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed